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Why Can Capsaicin Relieve Pain?

As an important seasoning, chilli peppers have been popular for a long time. However, there are few mammals except humans that love spicy food in nature, because the heat produced by chilli peppers is not a taste, but a pain. When people eat chilli peppers, capsaicin and pain sensation will stimulate the brain to release dopamine, making people feel euphoric and excited, as well as increasing their appetite. When people fall in love with this feeling, they will increasingly like spicy food. Chilli capsaicin, also known as capsicum capsaicin, has a variety of pharmacological effects, such as analgesia, anti-inflammatory, anti-pruritus, sterilization, treatment of frostbite, drug addiction and rheumatism. Capsaicin is the main ingredient in some clinical painkillers.

Ⅰ. Analysis of the causes of capsaicin for pain relief

There is a chemical substance distributed along the pathway of nociceptive receptors and neurotransmitters. This chemical such as the pava oc powder can be activated by a variety of pain factors, which can lead to various pain sensations, especially inflammatory and heat-sensitive pain. Chilli capsaicin is one of the pain factors. Chilli capsaicin continues to stimulate TRPV1, which makes nerve cells release pain-causing substances, deplete these substances in cells. Even if there is pain stimulation at this time, nerve cells can no longer release TRPV1, so the pain is inhibited. Therefore, when using capsicum capsaicin analgesia, people often feel ache on the skin first for a while, but then the pain will be relieved gradually. When there is inflammation, chilli capsaicin not only helps relieve pain, the local vasodilation and increased blood flow can also increase tissue repair capacity. After the injury part is repaired, the release of inflammatory factors is reduced or stopped, so as to achieve the purpose of pain relief and treatment.

Ⅱ. Precautions for using capsaicin

DAYU Chemical has high quality oleoresin capsicum powder. It is important to note that chilli capsaicin analgesia is only suitable for inflammatory (non-infectious) and injury-causing pain. It has no effect on neuropathological pain, trigeminal neuralgia, visceral pain and gastrointestinal colic. This is relevant with the fact that nerve fibers in the gastrointestinal tract are different from those in the skin, muscles, and joints, so if you eat chill when you have a stomachache, the pain will get more serious. At present, capsicum capsaicin is mainly made into external preparations, including plaster applied, ointment applied, gel, etc., which can be used for local pain relief treatment of arthritis, joint pain and fall injury. Generally, we take appropriate amount of ointment and apply 3 to 4 times a day. Wash your hands before and after applying. Do not rub the eyes and mucous membrane after using the medicine with hands. If the local pain does not relieve after one week of use, please consult physicians.

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